Monday, December 17, 2012


Beta-alanine combines with the amino acid, histidine, to form carnosine.

Carnosine (a component of vitamin B3) helps muscle generate greater forceful contractions for a longer period. The result is increases in strength and endurance. The end result is mass gains.

Beta-alanine with creatine seems to result in more muscle and less fat than subjects taking creatine alone.

The unfortunate side effect of beta-alanine is flushing and tingling (paresthesia) . Some take beta-alanine in small doses throughout the day to avoid the tingling.

Dosage is 2-3g with your pre- and post-workout shakes. The optimal dose seems to be 3.2 grams per day.

1 Derave W, Everaert I, Beeckman S, et al. Muscle carnitine metabsm and beta-alanine supplementation in relation to exercise and training. Sports Med. 2010;40(3):247-263.
2 Harris RC, Wise JA, Price KA, et al. Determinants of muscle carnitine content. Amino Acids. 2012 Feb 11. [Epub ahead of print]

3 Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids. 2006;30(3):279-289.

4 Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids. 2007;32(2):225-233.

5 Greenhaff PL, Bodin K, Soderlund K, Hultman E. Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Am J Physiol. 1994;266(5 Pt 1):E725-730.

6 Baguet A, Reyngoudt H, Pottier A, et al. Carnosine loading and washout in human skeletal muscles. J Appl Physiol. 2009;106(3):837-842.

7 Tallon MJ, Harris RC, Boobis LH, et al. The carnosine content of vastus lateralis is elevated in resistance-trained bodybuilders. Journal of Strength and Conditioning Research. 2005;19(4): 725–729.

8 Stellingwerff T, Decombaz J, Harris RC, Boesch C. Optimizing human in vivo dosing and delivery of β-alanine supplements for muscle carnosine synthesis. Amino Acids. 2012 Feb 23. [Epub ahead of print]

9 Baguet A, Everaert I, Hespel P, et al. A new method for non-invasive estimation of human muscle fiber type composition. PLoS One. 2011;6(7):e21956.

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